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Revisiting the Famous Twin Study

Article: Revisiting the Famous Twin Study


Health can feel amorphous sometimes. Eat better, exercise, lose weight… We often hear this general advice, but how much of a difference can this make if we’re already relatively healthy? And really… how long does it take to see results? With the current world spinning at a dizzying speed, we all want a guarantee that our choices are going to lead to results... and fast!


So how long does it take to see results after making a dietary change in generally healthy adults? According to a recent study from Stanford and University of California, about a month.


New twin study in JAMA 11/2023
The Twin study originally published in JAMA 11/2023

In a fascinating study by Landry et al, just published this month in the Journal Nutrition, Obesity and Exercise, researchers compared identical (mono-zygotic) twins, asking the question, is there a benefit to going fully plant based when compared to eating an unprocessed diet with organic meat, dairy and eggs?


JAMA open Twin Study

Now, whenever I read a nutrition study, I always ask myself, is this study being set up to fail? If we are comparing dietary interventions, are they on an equal playing field? Did the authors just compare a plant-based diet to a Standard American Diet (SAD)? No. With Professors Christopher Gardner of Stanford and Justin Sonnenburg of UC Palo Alto as co-authors, we can rest assured that they chose a fair comparison. Both groups consumed essentially the same thing, with only the addition of high quality meat, dairy and eggs in the omnivorous group.


“Guiding principles were reinforced: (1) choose minimally processed foods; (2) build a balanced plate with vegetables, starch, protein, and healthy fats; (3) choose variety within each food group; and (4) individualize these guidelines to meet preferences and needs“ (1).


So what happened? Both groups saw benefits from just cutting out the processed carbohydrates and added sugars, but the fully plant-based group did the best.


On the fully plant-based diet LDL cholesterol improved the most, fasting insulin levels went down by about 20% and they lost an average of 4.2 lbs more than the omnivorous group in just 8 weeks. And that was without asking participants to lose weight – they just did. Which begs the question, was it the weight loss or the reduction in saturated fat that improved the LDL cholesterol? The study can’t speak to that. I suspect that the answer is likely: both.


Twin study outcomes

“Although our findings suggest that vegan diets offer a protective cardiometabolic advantage compared with a healthy, omnivorous diet, excluding all meats and/or dairy products may not be necessary because research suggests that cardiovascular benefits can be achieved with modest reductions in animal foods and increases in healthy plant-based foods compared with typical diets“ (1). Just another reason why I specialize in helping clients transition towards a plant predominant dietary pattern.


Looking to make the transition towards a plant predominant dietary pattern but not sure where to start? Want confirmation that your cholesterol is improving with the convenience of affordable at-home lab draws? Schedule your FREE new patient consult with Lifestyle Medicine Maine and make sure to check out our Black Friday offer, good until midnight on 12/31/2023.









References

  1. Cardiometabolic Effects of Omnivorous vs Vegan Diets in Identical TwinsA Randomized Clinical Trial. Landry et al. Journal of the American Medical Association (JAMA) (2023) https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2812392






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This is not medical advice

The Veggie Press (the Lifestyle Medicine Maine Blog) is not medical advice. The following information are meant for entertainment and education purposes only and should not be used to diagnose or treat any medical condition nor should they be used as a substitute for medical advice from a qualified, board-certified practicing clinician. Always consult your health care provider before making changes to your diet and/or lifestyle.

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